The Manchester Evening News report Victor Lindelof and Alex Telles are not in the Manchester United squad to face RB Leipzig tonight.
Both defenders played and shone in the 2-1 win against Paris Saint-Germain last week.
But both have apparently not been spotted with the squad ahead of the clash with last season’s semi-finalists.
If the pair are both out, it may mean another run-out for Axel Tuanzebe, another who impressed in Paris.
It also makes it unlikely Ole Gunnar Solskjaer will revert to the back five he used at Parc des Princes.
Tuanzebe and Harry Maguire is the likely central defensive partnership, with Luke Shaw and Aaron Wan-Bissaka rounding off the back four.
We’ve also picked out some of the best reaction from United fans to the early team news report.
It’s unlikely we’ll know for sure whether the defensive duo are confirmed out until closer to kick off but that hasn’t stopped plenty of supporters on Twitter giving their thoughts…